Enlarged Stomach In Ultrasound

The identification of genes and cell handling mother in addition to therapies for glaucoma

Ophthalmic Research Unit Santiago Grisolia Peset Doctor's Hospital in Valencia, is developing for several years a research that aims to identify genes and molecules involved in glaucoma. In addition, researchers are working to isolate and cultivate stem cells trabeculum the network through which removes the eye's aqueous humor, and at the block in primary open angle glaucoma (POAG), causes a rise in blood eye.

Trabecular meshwork María Dolores

Pinazo-Duran, Ophthalmic Research Unit with the center, who participated in the meeting on glaucoma, DM has explained that "the trabecular meshwork is a structure that is located in the anterior chamber angle of eye, getting in the way of drainage of aqueous humor. Anatomical and physiological characteristics suggest that the alterations are associated with increased intraocular pressure and POAG. In fact, the trabecular meshwork of glaucoma patients show obvious morphological changes: thickening of the trabecular beams and yuxtacanalicular tissue, endothelial cell loss and abundant deposit material (calcium and pigment granules). " With these modifications, vary the conditions of drainage of aqueous humor from the anterior chamber into Schlemm's canal, "in direct relation to the alteration of the homeostasis of aqueous humor and increased intraocular pressure and thus, the establishment of POAG.

The idea of \u200b\u200bthis line of research in this laboratory, in collaboration with Deborah Burks, at Centro de Investigación Príncipe Felipe, Valencia, is to replace damaged cells in glaucomatous patient healthy cells.

Restoring

transit

With patient consent, researchers are getting trabecular tissue samples from different eyes scheduled for surgery hospitals in Valencia antiglaucomatous by trabeculectomy. For its part, the control group of samples is extracted from the eyes of donors after obtaining the corneal tissue for keratoplasty, dissecting the sclera ring remnant. "The goal is to trabecular meshwork cells that can be best implemented in the glaucomatous eye and thus restore the normal transit of the outer aqueous humor eye and, by extension, re-regulate the pressure. "

SOURCE: DiarioMedico.com